|
Product
Range & Product Grades
Microcrystalline Cellulose (MCC ) -IP / USP / Ph. Eur.
RanQ's
RANCEL brand MCC is manufactured from virgin wood -pulp specially
imported from paper mill with facility for manufacturing MCC grade
wood-pulp. RanQ MCC is spray dried with excellent flow properties
. RanQ MCC meets standards set in USP/NF, Ph.Eur. & BP. However
equally important are the in-house specifications for parameters
like Degree of Polymerization (DOP), particle size distribution,
bulk density, moisture content and flow properties . At RanQ all
these parameters have been thoroughly analysed and inhouse limits
are in place to ensure optimum performance in terms of compressibility,
friability, hardness and D.T. in the end formulations. These properties
are not enumerated in the pharmacopoeia's but are vital for the
consistent performance of MCC as binder/filler. The grades of RANCEL
MCC are given below, but RanQ can tailor make MCC as per the formulators
limits for the various physical parameters.
MCC -GRADES
| Grade |
Av.
Particle size |
Loss
on drying |
Remarks
(Micron) |
| RQ
101 |
50 |
<
6.0 % |
Small
Particle |
| RQ
102 |
90 |
<
6.0 % |
Large
Particle with superior flow properties |
| RQ
200 |
200 |
<6.0
% |
Coarse
particle for formulations which have high content, poor
flow actives |
| RQ
112 (S) |
50 |
<
3.5 % |
Low
L.O.D. |
| RQ
112 |
50 |
<
1.5 % |
Low
L.O.D. |
| RQ
301 |
50 |
<
6.0 % |
High
Bulk Density |
| RQ
302 |
100 |
<
6.0 % |
High
Bulk Density |
|
Sodium
Starch Glycollate (SSG )
RanQ's
RANJEL is manufactured only from Potato Starch. It has been
conclusively proved that swelling properties of SSG manufactured
from Potato Starch are far superior to that manufactured from maize,
rice or tapioca starch . While other starches are readily available
in India, Potato starch is imported from Holland. Ranjel is
manufactured under controlled reaction parameters to ensure batch
to batch consistency of swelling and hydration properties which
in turn would ensure consistent D.T. in end formulations . RanQ's
SSG meets standards set in USP/NF, Ph.Eur., BP. & compares favorably
with the best available in the world markets but for the price which
is competitive.
Co-processed
Excipients
RanQ
has made pioneering efforts in introducing co-processed excipients
with the major advantages of elimination of wet granulation production
stages , premixed excipients avoiding the need for keeping and adding
various excipients required for the formulation & the synergetic
effect of having a homogenous mix. RanQ's Co-processed excipients
would provide for sturdy formulations and the grades mentioned below
are particularly advantageous for Mouth dissolving/Dispersible formulations.
A study made for RanQ's Co- processed excipients is available on
request. The following grades are approved for production by the
India FDA are being regularly used in commercial productions.
RanExplo
- C : MCC + Colloidal Silicon Dioxide + Crospovidone
RanExplo - S : MCC + Colloidal Silicon Dioxide + Sodium Starch Glycollate
Note
|